Venclexta is a medication used to treat certain types of chronic lymphocytic leukemia (CLL) and acute myeloid leukemia (AML). The active ingredient in Venclexta is venetoclax, which belongs to a class of drugs called BCL-2 inhibitors. Venclexta works by blocking the BCL-2 protein, which helps cancer cells survive, leading to the death of these cells.
Dosage and Administration:
Venclexta is available in tablet form with different strengths, and the dosage and treatment schedule may vary depending on the type of leukemia being treated. The dosage is determined by your doctor, and it’s important to follow their instructions carefully.
For Chronic Lymphocytic Leukemia (CLL):
- The initial dose is gradually increased over 5 weeks to reach the recommended daily maintenance dose.
- The recommended daily maintenance dose for most patients is 400 mg, taken orally once daily.
- The treatment duration may vary, and it is usually continued as long as it is effective and tolerated.
For Acute Myeloid Leukemia (AML):
- The dosage and treatment schedule for AML may differ from CLL. Your doctor will determine the appropriate dose and treatment duration based on your specific situation.
It is important to take Venclexta exactly as prescribed by your doctor. The tablets should be swallowed whole with a glass of water and can be taken with or without food.
Potential Side Effects:
Venclexta may cause side effects, and the severity and occurrence may vary from person to person. Common side effects may include nausea, diarrhea, vomiting, constipation, fatigue, muscle or joint pain, fever, and cough. Inform your doctor if any side effects become severe or persistent.
Venclexta may also cause serious side effects such as low white blood cell counts, increased risk of infection, tumor lysis syndrome (a condition caused by the rapid breakdown of cancer cells), and other potential adverse effects. Your doctor will monitor your blood counts and overall health closely during treatment.
Precautions:
Before taking Venclexta, inform your doctor about your medical history, including any other medical conditions you have and any medications you are currently taking, including over-the-counter drugs, vitamins, and herbal supplements.
Venclexta can interact with other medications, so it’s important to disclose all your current medications to your doctor to avoid potential interactions.
Venclexta may cause harm to an unborn baby, so it is essential to use effective contraception during treatment and for at least 30 days after the last dose if you or your partner can become pregnant.
In conclusion, Venclexta is a medication used to treat specific types of chronic lymphocytic leukemia (CLL) and acute myeloid leukemia (AML). It contains the active ingredient venetoclax, which works by blocking the BCL-2 protein to promote cancer cell death. The dosage and treatment schedule will be determined by your doctor based on your specific condition. It’s important to take Venclexta exactly as prescribed and inform your doctor of any other medications you are taking. Be aware of potential side effects and seek medical advice if needed.