oral tyrosine kinase inhibitor that works by blocking specific abnormal proteins in cancer cells, inhibiting their growth and division. It is primarily used in the treatment of certain types of leukemia, such as chronic myeloid leukemia (CML) and acute lymphoblastic leukemia (ALL), as well as gastrointestinal stromal tumors (GISTs).
Dosage and Administration:
The dosage of Imatinib can vary depending on the type and stage of cancer being treated, as well as individual patient factors. It is crucial to follow the prescribed dosage and instructions provided by your doctor or healthcare professional.
Imatinib is typically available in tablets of various strengths, including 100 mg and 400 mg. The dosage and frequency of administration will be determined by your healthcare provider based on your specific condition. Generally, the recommended starting dose for CML is 400 mg once daily, while for GISTs, it is 400 mg to 600 mg daily, divided into multiple doses.
Imatinib tablets should be taken with a full glass of water, either with or without food. It’s important to swallow the tablets whole and not crush or chew them unless directed otherwise by your doctor.
Usage and Precautions:
It is essential to strictly adhere to the prescribed regimen and not alter the dosage or stop taking Imatinib without consulting your healthcare provider. Even if you start feeling better, it is crucial to complete the full course of treatment.
Certain precautions should be considered when using Imatinib:
- Inform your healthcare provider about any other medications, supplements, or herbal products you are taking, as they may interact with Imatinib.
- Discuss any existing medical conditions, especially liver or kidney problems, heart disease, bleeding disorders, or fluid retention, with your doctor before starting Imatinib.
- Regular monitoring and follow-up visits will be necessary to assess the response to treatment and manage any potential side effects.
- Imatinib may cause side effects such as nausea, diarrhea, muscle cramps, fatigue, skin rash, and fluid retention. If you experience severe or persistent side effects, inform your healthcare provider.