Temodal (temozolomide) is an anticancer medication primarily used to treat certain types of brain tumors, including glioblastoma multiforme (GBM) and anaplastic astrocytoma. It belongs to a class of drugs called alkylating agents, which work by interfering with the growth of cancer cells.
Dosage and Administration:
Temodal is available in 250 mg capsules. The dosage and treatment schedule will be determined by your doctor based on your specific condition. It is important to follow your doctor’s instructions and the prescribed dosage.
For the treatment of glioblastoma multiforme, the usual recommended dose is 75 mg/m² of body surface area taken once daily. The treatment is typically administered for 42 days concomitantly with radiotherapy, followed by a maintenance phase of 150 mg/m² once daily for 5 consecutive days, repeated every 28 days. This cycle is repeated for several treatment cycles, as determined by your doctor.
For the treatment of anaplastic astrocytoma, the dosage and treatment schedule may vary. Your doctor will determine the appropriate dosage and duration based on your specific situation.
Temodal capsules should be swallowed whole with water. It is important not to open, crush, or chew the capsules, as this can affect the way the medication is absorbed by the body.
Precautions:
Before starting Temodal, inform your doctor about any other medical conditions you have, such as liver or kidney disease, or a history of low blood cell counts. It is also important to disclose any other medications you are taking, including over-the-counter drugs, vitamins, and herbal supplements, as they may interact with Temodal.
During treatment with Temodal, your doctor will monitor your blood cell counts regularly to ensure they remain within the appropriate range. This medication may cause a decrease in the number of white blood cells, red blood cells, and platelets. If you experience any signs of infection (such as fever, sore throat, or cough), unusual bruising or bleeding, or symptoms of anemia (such as fatigue, pale skin, or shortness of breath), contact your doctor immediately.
Possible Side Effects:
Temodal can cause various side effects, which can vary from person to person. Common side effects may include nausea, vomiting, loss of appetite, constipation, headache, fatigue, and hair loss. These side effects are usually temporary and manageable.
Serious side effects are rare but can occur. These may include allergic reactions, severe skin reactions, liver problems, or signs of infection. If you experience any severe or persistent side effects, inform your doctor promptly.
In conclusion, Temodal (temozolomide) is an anticancer medication used to treat specific types of brain tumors. It is available in 250 mg capsules and the dosage and treatment schedule will be determined by your doctor. It is important to take Temodal as prescribed and follow your doctor’s instructions. Report any side effects or concerns to your healthcare provider.