Temodal (Temozolomide) is a medication used for the treatment of certain types of brain tumors, specifically glioblastoma multiforme (GBM) and anaplastic astrocytoma. It belongs to the class of chemotherapy drugs known as alkylating agents. The active ingredient in Temodal is temozolomide.
Dosage and Administration:
Temodal is available in 100 mg capsules. The dosage and treatment schedule may vary depending on the specific condition being treated and individual patient factors. It is crucial to follow the instructions provided by your doctor or healthcare professional. Do not adjust the dosage or stop taking Temodal without consulting your doctor.
The typical starting dose for adults with glioblastoma multiforme is 75 mg/m² once daily for 42 consecutive days. This is usually followed by a 4-week break in treatment, after which the cycle may be repeated depending on the response to therapy.
For patients with anaplastic astrocytoma, the starting dose is generally 150 mg/m² once daily for 5 consecutive days every 28 days. The treatment may be repeated in subsequent cycles as determined by the physician.
Temodal capsules should be swallowed whole with a glass of water, preferably on an empty stomach. If you have difficulty swallowing, you may open the capsule and sprinkle the contents on a spoonful of soft food (e.g., applesauce), but it should be consumed immediately without chewing.
It is important to take Temodal at the same time each day to maintain a consistent level of the medication in your body.
Possible Side Effects:
Like any chemotherapy medication, Temodal can cause side effects. Common side effects may include nausea, vomiting, fatigue, constipation, loss of appetite, headache, hair loss, and low blood cell counts (which can increase the risk of infection, bleeding, and fatigue). These side effects may vary in severity and duration from person to person.
It is important to report any severe or persistent side effects to your doctor. They can provide guidance on managing these side effects or adjust the treatment if necessary.
Precautions:
Before taking Temodal, inform your doctor about any pre-existing medical conditions you have, including liver or kidney problems. It is also important to disclose all medications, vitamins, or herbal supplements you are taking, as they may interact with Temodal.
Temodal can have harmful effects on a developing fetus, so it should not be used during pregnancy unless clearly necessary. Effective contraception should be used by both males and females during treatment and for a period after treatment ends.
In conclusion, Temodal (Temozolomide) is a chemotherapy medication used for the treatment of glioblastoma multiforme and anaplastic astrocytoma. It is available in 100 mg capsules and should be taken according to the dosage and schedule prescribed by your doctor. Common side effects may occur, and it is important to report any severe or persistent side effects to your doctor. Precautions should be taken during pregnancy, and it is important to discuss any existing medical conditions or medications with your doctor before starting treatment with Temodal.